Dosing Guide 01 Microdoses Take 100mg for 4 days on and 3 days off. 02 Release Time It takes approximately 45 minutes to kick in. 03 Effects Increased mental clarity and focus. Little to no physical effects. 01 Macrodoses Macrodoses should be taken on an as-needed basis. 02 Release Time It takes approximately 1-2 hours to kick in. 03 Effects Euphoria, heightened senses and awareness to your environment. Ready to shop? Shop Now